I always stay in Alexandria when I visit D.C. for an extended period of time and hop on the metro.
I went cheap and stayed at a Comfort Inn on Duke Street in Alexandria and it was nice for the price. Clean and they gave me a coupon to the IHOP in their parking lot. If you want easy metro access, there's one on Van Dorn right at a metro stop.
Alexandria Virginia Hotels ~ Washington DC Lodging
From all of my hotel experience though, you can never go wrong with a Hampton Inn. I've been to about 10 and never saw a bad one and they have an awesome breakfast buffet.
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